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What is Autoimmune Disease and How Does it Develop?

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About What is Autoimmune Disease and How Does it Develop?

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Autoimmune disease occurs when the immune system attacks its own cells and tissues. In this video, you'll learn how autoimmune disease develops, including how autoreactive B and T-cells form, escape immune tolerance, and get activated through molecular mimicry, bystander activation and epitope spread. Autoimmune Diseases can affect one organ, as in Type I Diabetes or many organs, as in Lupus. More than 100 autoimmune disorders affect 5-10% of people worldwide. 📥 Download the free PDF guide → https://www.clevalab.com/resources 📖 Read the blog post → https://clevalab.com/post/what-are-autoimmune-diseases 🌏 https://www.clevalab.com 👉 Watch next: Growing Organs → https://youtu.be/jSWwDCNNtrE ✉️ Join the ClevaLab Community for free guides and updates on the upcoming courses → https://www.clevalab.com/email-subscription _Correction: The heading at 5:12 contains a typo ("Epitope Spead" instead of "Epitope Spread")._ SOCIAL MEDIA LINKS Twitter: https://twitter.com/_ClevaLab Instagram: https://www.instagram.com/_clevalab Pinterest: https://www.pinterest.com.au/ClevaLab Tiktok: https://www.tiktok.com/@clevalab Facebook: https://www.facebook.com/ClevaLab CHAPTERS: 00:00 What is an Autoimmune Disease? 00:13 Types of Autoimmune Disease 00:38 Autoimmune Disease Risk 00:59 Autoimmune Disease Symptoms 01:15 Autoimmune Disease Diagnosis 01:27 Autoantibodies 01:53 Autoimmunity and Immune Tolerance 02:27 Role of Antibodies 02:33 B-Cell Development 03:14 T-cell Development 04:04 Activation of Autoreactive B & T-Cells 04:10 Molecular Mimicry 04:35 Bystander Activation 05:11 Epitope Spread 06:40 Viral Persistence 06:59 Symptoms Depend on Target Antigen 07:79 Autoimmune Disease Treatment #ClevaLab #autoimmune #autoimmunediseases

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