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Vaccination in pregnancy

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UK CoViD symptom study https://covid.joinzoe.com https://covid.joinzoe.com/data#levels-over-time Joint Committee on Vaccination and Immunisation (JCVI) pregnancy advice Citing US data https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/vsafepregnancyregistry.html https://www.gov.uk/government/news/jcvi-issues-new-advice-on-covid-19-vaccination-for-pregnant-women 90,000 pregnant women have been vaccinated, mainly with mRNA vaccines including Pfizer-BioNTech and Moderna, without any safety concerns being raised. Preferable for pregnant women in the UK to be offered the Pfizer-BioNTech or Moderna vaccines where available. There is no evidence to suggest that other vaccines are unsafe for pregnant women, but more research is needed. still advises that pregnant women should discuss the risks and benefits of vaccination with their clinician Green book reference, https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/978508/Green_book_chapter_16April2021.pdf US data https://covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases https://covid.cdc.gov/covid-data-tracker/#hospitalizations Brazil Vinicius Speaking from Brazil here. The situation is absolutely out of control. There are thousands of people dying without even get the chance to be treated. We need help, our goverment simply doesn't do anything about it. I personally know more then 15 people that died from COVID. Deaths, 371,889 https://www.bbc.co.uk/news/world-latin-america-56696907 Deaths in under 9s, 852 Including 518 under I year 0.58% of Brazil's 345,287 Covid deaths to date have been of 0-9 year olds More than 2,000 children Not all from MIS Up to 6 weeks after acute infection Dr Fatima Marinho from the University of São Paolo Childhood deaths underreported 10 times more deaths by unexplained respiratory syndrome than in previous years Actual deaths, 2,060 children under nine years old, including 1,302 babies Factors High case numbers Limited testing in children Poverty and access to care Crowded poor accommodation Background malnutrition Late diagnosis and care Currently no vaccination under 16 years Differential presentation A child has a lot more diarrhoea, a lot more abdominal pain, and chest pain, than the classic Covid picture. Because there is a delay in diagnosis, when the child arrives at the hospital they are in a serious condition and can end up complicating - and dying https://www.rcpch.ac.uk/key-topics/covid-19 https://www.rcpch.ac.uk/resources/advice-parents-young-people-during-coronavirus-posters Chile, vaccination contradiction? Population 19 million Well-developed public health system Remote area coverage Well-practiced vaccination pathways https://www.washingtonpost.com/world/2021/04/16/chile-coronavirus-china-sinovac-vaccine/ https://abcnews.go.com/Health/wireStory/big-chile-study-finds-chinese-vaccine-slashes-covid-77120616 Israel, UK, Chile, US Population, 19 million First dose, 7.5 million Second dose, 5 million But https://www.worldometers.info/coronavirus/?utm_campaign=homeAdvegas1? Factors Pandemic fatigue Summer vacation travel New variants Chinese vaccine Leonila Ferreira, ITU, Concepción Patients younger on average than during the first wave Continuing to let people travel abroad was a grave error It introduced new variants which Chile has been slow to detect and contain 87% Sinovac’s CoronaVac data 60 million doses contracted over 3 years (also some Pfizer) 10.5 million people followed, Feb. 2 to April 1 of whom 1.5 million first dose 2.5 million second dose Two weeks after second dose (28 days between primary and booster doses) Symptomatic disease reduced by 67% Deaths reduced by 80% Hospitalizations reduced by 85% ICU admission by reduced by 89% Much lower after only one dose Hospitals still stretched Thinking about a third dose Santiago locked down again Now First dose, 40% Second dose, 27% Down to 48 year olds Sharp decrease in over 70 hospitalizations Sustained rise in under 59s https://www.rcpch.ac.uk/resources/advice-parents-young-people-during-coronavirus-posters Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine https://osf.io/a9jdq/

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