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Is Life Becoming Programmable? | AlphaFold & CRISPR Explained Analytics Table

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**Is Life Becoming Programmable? | AlphaFold & CRISPR Explained** For most of human history, biology was something that happened to us. Our genes were fixed. Disease written into our DNA was permanent. That's changing — faster than most people realise. In this video, I break down two technologies that are quietly rewriting what it means to be human: 🔬 **AlphaFold** — the AI that predicted 200 million protein structures in one year, after humanity mapped only 150,000 in six decades. What it means for Alzheimer's, cancer, and drug discovery. ✂️ **CRISPR** — the gene-editing tool that cured a woman of sickle cell disease and built a personalised therapy for a single infant in months. Plus the scandal that shook the scientific world. But this isn't just a good news story. I also cover the $2M price tag, the embryo experiment that horrified scientists, and the question nobody has fully answered — where is the line between treating disease and designing humans? --- **Research & Citations** - John Kendrew & protein structure: https://youtu.be/P_fHJIYENdI?si=7eG7wJ9p3HtI5QT- - AlphaFold applications in disease: https://www.drugdiscoverytrends.com/7-ways-deepmind-alphafold-used-life-sciences/ - AlphaFold & Alzheimer's: Pinheiro, F., Santos, J., & Ventura, S. (2021). Journal of Molecular Biology, 433(20), 167059. https://doi.org/10.1016/j.jmb.2021.167059 - AlphaFold & COVID-19: Torres, J., Pervushin, K., & Surya, W. (2024). Computational and Structural Biotechnology Journal, 23, 3730–3740. https://doi.org/10.1016/j.csbj.2024.10.021 - AlphaFold strengths & limitations: https://www.ebi.ac.uk/training/online/courses/alphafold/an-introductory-guide-to-its-strengths-and-limitations/ - AlphaGenome explained: https://youtu.be/C0gErQtnNFE?si=W3Z4DUE5TL6W3cSD - Victoria Gray / sickle cell cure: https://www.npr.org/sections/health-shots/2021/12/31/1067400512/first-sickle-cell-patient-treated-with-crispr-gene-editing-still-thriving - Baby KJ / personalised CRISPR therapy (CHOP): https://www.chop.edu/news/worlds-first-patient-treated-personalized-crispr-gene-editing-therapy-childrens-hospital - Baby KJ (NIH): https://www.nih.gov/news-events/news-releases/infant-rare-incurable-disease-first-successfully-receive-personalized-gene-therapy-treatment - He Jiankui CRISPR embryo scandal: https://www.science.org/content/article/did-crispr-help-or-harm-first-ever-gene-edited-babies - Jennifer Doudna on CRISPR ethics: https://youtu.be/0OXaanDHENI?si=Km2i50cB6DNKKDbT --- **Credits** last footage - https://youtu.be/0OXaanDHENI?si=t2RWmDpokss-2c92 Thank you! @CleoAbram #CRISPR #AlphaFold #GeneEditing #ScienceExplained #FutureOfMedicine

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