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Explore A Disease's Guide to World Domination with 1,675,325 views, 19,387 likes, and 1,502 comments. Experience the impact of this video content that has captured audience attention.

There's something surprising that helps determine how damaging a disease is: distance. LEARN MORE ************** To learn more about this topic, start your googling with these keywords: - Direct transmission: occurs when a pathogen is transmitted to a new host by physical or close contact - Virulence: the degree of damage a pathogen causes its host CREDITS ********* Script Writer: Kate Yoshida Script Editor: Alex Reich Video Illustrator: Ever Salazar Video Director: Kate Yoshida and Alex Reich Video Narrator: Kate Yoshida With Contributions From: Henry Reich, Emily Elert, Peter Reich, David Goldenberg Music by: Nathaniel Schroeder MinuteEarth is produced by Neptune Studios LLC https://neptunestudios.info SUPPORT MINUTEEARTH ************************** If you like what we do, you can help us!: - Become our patron: https://patreon.com/MinuteEarth - Our merch: https://dftba.com/minuteearth - Our book: https://minuteearth.com/books - Share this video with your friends and family - Leave us a comment (we read them!) OUR LINKS ************ Youtube | https://youtube.com/MinuteEarth TikTok | https://tiktok.com/@minuteearth Twitter | https://twitter.com/MinuteEarth Instagram | https://instagram.com/minute_earth Facebook | https://facebook.com/Minuteearth Website | https://minuteearth.com Apple Podcasts| https://podcasts.apple.com/us/podcast/minuteearth/id649211176 REFERENCES ************** Blanquart, F., et al. (2016). A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in Uganda. Elife 5: 5. de Roode, J.C., Yates, A.J., & Altizer, S. (2008). Virulence-transmission trade-offs and population divergence in virulence in a naturally occurring butterfly parasite. Proceedings of the National Academy of Science 105: 7489-7494 Ewald, P.W. (1983). Host-parasite relations, vectors, and the evolution of disease severity. Annual Reviews Ecology & Systematics 14: 465-485 Ewald, P.W. (1991). Waterborne transmission and the evolution of virulence among gastrointestinal bacteria. Epidemiology & Infection 106: 83-119. Ewald, P.W. (1991). Transmission modes and the evolution of virulence: with special reference to cholera, influenza, and AIDS. Human Nature 2: 1-30. Galvani, A.P. (2003) Epidemiology meets evolutionary ecology. Trends in Ecology & Evolution 18: 132-139. Lipsitch, M. & Moxon, E.R. (1997). Virulence and transmissibility of pathogens: what is the relationship? Trends in Microbiology 5: 31-37.

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