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Sperm Parameters Before and After COVID-19 mRNA Vaccination https://jamanetwork.com/journals/jama/fullarticle/2781360 https://www.dw.com/en/covid-vaccine-the-unfounded-tale-of-infertility/a-58753946 Reproductive toxicity was not evaluated in the clinical trials SARS-CoV-2 has been associated with decreases in sperm parameters We assessed sperm parameters before and after mRNA vaccine administration Volunteers aged 18 to 50 years, n = 45 Scheduled for mRNA COVID-19 vaccination Participants provided a semen sample after 2 to 7 days of abstinence prior to receiving the first vaccine dose Then median 75 days after the second Semen analyses semen volume, sperm concentration, sperm motility, and total motile sperm count Results December 17, 2020 to January 12, 2021 Of the 45 men 21 (46.7%) received BNT162b2 (Pfizer) 24 (53.3%) mRNA-1273 (Moderna) Baseline Median sperm concentration, 26 million per ml Total motile sperm count, 36 million After second vaccine dose Median sperm concentration, 39 million per ml Total motile sperm count, 44 million Semen volume and sperm motility also significantly increased Eight of the 45 men were oligospermic before the vaccine Of these 8, 7 men had increased sperm concentration to normozoospermic Men with oligospermia did not experience further decline No man became azoospermic after the vaccine Discussion No significant decreases in any sperm parameter among small cohort of healthy men Vaccines contain mRNA and not the live virus, unlikely that the vaccine would affect sperm parameters Reasons for the increases Magnitude of change is within normal individual variation May be influenced by regression to the mean Increased abstinence time before the second sample. Study’s time frame encompasses the full life cycle of sperm https://msdh.ms.gov/msdhsite/_static/14,21994,420,873.html

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