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Explore Duchenne Muscular Dystrophy (DMD) Explained: Symptoms, Causes, and Disease Progression with 9,156 views, 146 likes, and 1 comments. Experience the impact of this video content that has captured audience attention.

Duchenne muscular dystrophy (DMD) is a rare X-linked recessive genetic muscle disorder caused by a mutation in the dystrophin gene, leading to complete loss of the dystrophin protein — the key structure that protects muscle cells from damage. Without dystrophin, muscle fibers tear during contractions, causing progressive muscle weakness. Symptoms usually appear in early childhood: repeated falls, tiptoe walking, calf hypertrophy, Gowers sign (using hands to rise from the floor), bent knees, protruding abdomen, and scoliosis. Weakness starts in the proximal muscles and gradually affects the respiratory and cardiac muscles. By age 12, most patients require a wheelchair; by the late teens or early 20s, they need breathing and heart support. Sadly, life expectancy is often in the 20s or 30s. This video covers the cause, symptoms, inheritance, and disease progression of Duchenne muscular dystrophy — essential for medical students, healthcare learners, and anyone wanting to understand this inherited muscle disease. Timestamps: 00:04 Introduction 00:17 Gene affected 00:27 Dystrophin 01:10 Without dystrophin 01:30 Age of onset and symptoms 02:22 Illness progression Check out Udemy Course Anatomy of a Cell https://www.udemy.com/course/anatomy-of-a-cell/?referralCode=F4C0ECBF03912377DA35 🎥 Related VB Anatomy Videos: Cell-Part 1: Cellular Foundations: Nucleus and Plasma Membrane - https://youtu.be/iBdwp2o-dIM?si=RMWT8MUMGfoCvn2m #DuchenneMuscularDystrophy #DMD #XLinkedRecessiveDisorder #DystrophinGeneMutation #DystrophinProteinDeficiency #MuscleWeakness #ProgressiveMuscleDegeneration #ProximalMuscleWeakness #GowersSign #HypertrophiedCalves #Scoliosis #TiptoeWalking #WheelchairByAge12 #RespiratoryMuscleWeakness #CardiacMuscleWeakness #LifeExpectancyInDMD #SymptomsOfDuchenneMuscularDystrophy #SignsOfDMD #MuscularDystrophyDiseaseProgression #GeneticMuscleDisorder #InheritedMuscleDisease

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