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Visit https://brilliant.org/scishow/ to get started learning STEM for free. The first 200 people will get 20% off their annual premium subscription and a 30-day free trial. For some people who stop taking an SSRI or SNRI antidepressant, they can get a weird side effect called brain zaps. And even though we've known about them for decades, we still don't know exactly why brain zaps happen. Hosted by: Hank Green (he/him) ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Adam Brainard, Alex Hackman, Ash, Benjamin Carleski, Bryan Cloer, charles george, Chris Mackey, Chris Peters, Christoph Schwanke, Christopher R Boucher, DrakoEsper, Eric Jensen, Friso, Garrett Galloway, Harrison Mills, J. Copen, Jaap Westera, Jason A Saslow, Jeffrey Mckishen, Jeremy Mattern, Kenny Wilson, Kevin Bealer, Kevin Knupp, Lyndsay Brown, Matt Curls, Michelle Dove, Piya Shedden, Rizwan Kassim, Sam Lutfi ---------- Looking for SciShow elsewhere on the internet? SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/ TikTok: https://www.tiktok.com/@scishow Twitter: http://www.twitter.com/scishow Instagram: http://instagram.com/thescishow Facebook: http://www.facebook.com/scishow #SciShow #science #education #learning #complexly ---------- Sources https://www.who.int/en/news-room/fact-sheets/detail/depression https://www.britannica.com/science/synapse https://www.cdc.gov/nchs/products/databriefs/db377.htm https://www.nytimes.com/2022/11/08/well/mind/antidepressants-effects-alternatives.html https://www.mayoclinic.org/diseases-conditions/depression/in-depth/maois/art-20043992 https://www.mayoclinic.org/diseases-conditions/depression/in-depth/ssris/art-20044825 https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970 https://magazine.medlineplus.gov/article/commonly-prescribed-antidepressants-and-how-they-work https://www.ncbi.nlm.nih.gov/books/NBK557791/ https://www.ncbi.nlm.nih.gov/books/NBK470212/ https://www.tandfonline.com/doi/epdf/10.1080/17522439.2018.1469163?src=getftr https://www.aafp.org/pubs/afp/issues/2006/0801/p449.html https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)32802-7/fulltext https://pubmed.ncbi.nlm.nih.gov/19588448/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630974 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410405 https://www.nature.com/articles/s41380-022-01661-0 https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2013.00045/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076339 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763983 https://pubmed.ncbi.nlm.nih.gov/19442174 https://pubmed.ncbi.nlm.nih.gov/10889545/ https://www.nature.com/articles/s41380-023-02090-3 https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.20230574 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC181142 https://www.sciencedirect.com/science/article/pii/S0306460318308347 https://pubmed.ncbi.nlm.nih.gov/29758951/ https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0447.1989.tb08578.x https://www.aafp.org/pubs/afp/issues/2006/0801/p449.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864293 https://journals.lww.com/psychopharmacology/fulltext/2010/02000/effects_of_the_serotonin_1a,_2a,_2c,_3a,_and_3b.3.aspx https://www.sciencedirect.com/science/article/pii/S0306460319309001 https://karger.com/pps/article/87/4/195/283079/Withdrawal-Symptoms-after-Serotonin-Noradrenaline https://pubmed.ncbi.nlm.nih.gov/15989562 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733524 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404667 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342590 https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bph.12720 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859674 https://pubmed.ncbi.nlm.nih.gov/30177236 https://pubmed.ncbi.nlm.nih.gov/29758951 https://pubmed.ncbi.nlm.nih.gov/30605268 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485546/ https://pubmed.ncbi.nlm.nih.gov/35144325 Image Sources https://www.gettyimages.com https://commons.wikimedia.org/wiki/File:Fluoxetine_20mg_with_Packet.jpg https://commons.wikimedia.org/wiki/File:Moclobemide_failure.png https://commons.wikimedia.org/wiki/File:Iproniazid.svg

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