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Four DNA Studies Just Rewrote What We Know About Neanderthal Ancestry! Analytics Table
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Roughly two percent of every non-African genome alive today is Neanderthal. Yet the Neanderthal Y chromosome is extinct everywhere on Earth, and Neanderthal mitochondrial DNA is gone. No man alive carries an unbroken Y descended from a Neanderthal father. This documentary follows the four genetic studies (Mendez 2016, Posth 2017, Petr 2020, Iasi 2024) that resolved the paradox. It shows why the Neanderthal we carry came down the female line, through Neanderthal mothers and hybrid daughters, not father to son. 📚 Sources: Mendez, F. L. et al. (2016). The Divergence of Neandertal and Modern Human Y Chromosomes. American Journal of Human Genetics, 98(4), 728–734. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833433/ Petr, M. et al. (2020). The evolutionary history of Neandertal and Denisovan Y chromosomes. Science, 369(6511), 1653–1656. https://www.science.org/doi/10.1126/science.abb6460 Posth, C. et al. (2017). Deeply divergent archaic mitochondrial genome provides lower time boundary for African gene flow into Neanderthals. Nature Communications, 8, 16046. https://www.nature.com/articles/ncomms16046 Iasi, L. N. M. et al. (2024). Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans. Science, 386(6727). https://pmc.ncbi.nlm.nih.gov/articles/PMC12184710/ Harris, K. & Nielsen, R. (2016). The Genetic Cost of Neanderthal Introgression. Genetics, 203(2), 881–891. https://pmc.ncbi.nlm.nih.gov/articles/PMC4896200/ Sankararaman, S. et al. (2014). The genomic landscape of Neanderthal ancestry in present-day humans. Nature, 507(7492), 354–357. https://www.nature.com/articles/nature12961
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