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2-Minute Neuroscience: Amygdala

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The amygdala is a collection of nuclei found in the temporal lobe; it is best known for its role in fear and threat detection, but its full range of functions is much more diverse. I discuss some of the major nuclei of the amygdala, a common scheme for the anatomical organization of the amygdalar nuclei, and some of the functions that have been associated with the amygdala ranging from threat detection to the processing of positive stimuli. 🧠 Take your learning further with my free, self-paced Introduction to Neuroscience course featuring my videos, articles, and hundreds of quiz questions: https://neuroscientificallychallenged.com/course If you're looking for accessible and entertaining ways to learn more about the brain, check out my books: 📚Your Brain, Explained: What Neuroscience Reveals About Your Brain and its Quirks: https://www.amazon.com/Your-Brain-Explained-Neuroscience-Reveals/dp/1473696569/ 📚Bizarre: The Most Peculiar Cases of Human Behavior and What They Tell Us About How the Brain Works: https://www.amazon.com/Bizarre-Peculiar-Cases-Human-Behavior/dp/139980121X/ TRANSCRIPT: Welcome to 2 minute neuroscience, where I simplistically explain neuroscience topics in 2 minutes or less. In this installment I will discuss the amygdala. The amygdala is a collection of nuclei found in the temporal lobe. There are two amygdalae, one in each cerebral hemisphere. The term amygdala means “almond,” referring to one of the most prominent nuclei of the amygdala that has an almond-like shape. The major nuclei of the amygdala include the lateral nucleus, basal nucleus, accessory basal nucleus, central nucleus, medial nucleus, and cortical nucleus. Each of these nuclei can also be partitioned into subnuclei. One common scheme for anatomically organizing the amygdala is to divide it into a basolateral region (made up of the lateral, basal, and accessory basal nuclei), and a cortico-medial region (made up of the cortical, medial, and central nuclei) . There are, however, other common ways of anatomically dividing the amygdala as well. The amygdala has traditionally been considered part of the limbic system, a group of structures linked to the processing of emotions. The amygdala has historically best been known for its role in processing fearful emotions. When a threatening stimulus is present in the environment, it is thought that the amygdala is also involved in identifying it as a threat and initiating a fight-or-flight response to it. More recent evidence, however, indicates that the amygdala is active during the processing of positive stimuli as well. Thus, it is now thought the amygdala’s role is more complex than that of a “threat detector.” It may be involved with assigning positive or negative value to stimuli and with the consolidation of memories that have a strong positive or negative emotional component. It is also still being explored in a variety of other behaviors ranging from addiction to social interaction. Thus, its functions are diverse and still not fully understood. REFERENCE: LeDoux J. The amygdala. Curr Biol. 2007 Oct 23;17(20):R868-74.

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