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Explore Injections versus infections, Pandemic update with 165,295 views, 5,912 likes, and 3,103 comments. Experience the impact of this video content that has captured audience attention.

UK https://coronavirus.data.gov.uk/details/cases Cases, + 35,475 (rolling 7 day average to 24 December) = 2,288,345 https://covid.joinzoe.com/data#levels-over-time Hospitalised, + 2,143 = 21,286 (1,529) Previous peak, 12 April = 21,683 Vaccinated, 616,933 Injections versus infections Deaths, + 316 = 70,752 Deaths, + 3,062 = 79,349 (COVID mentioned as one of the causes) Delays 14th December Cases, + 20,264 27th December Hospital admissions, 2,143 10.5% London Ambulance Service https://www.bbc.co.uk/news/uk-55462701 Emergency calls, 26 December = 7,918 Same as peak of first wave Up 2,500 on 26 December 2019 NHS England https://www.theguardian.com/society/2020/dec/27/hospitals-in-england-told-to-free-up-all-possible-beds-for-surging-covid-cases Entire health service, remain on highest alert, end of March Mobilise all of the available surge capacity over the coming weeks Surgical patients to local private facilities Discharge as many inpatients as possible Prepare for Nightingale openings London’s Royal Free Hospital Cancelled all non-emergency surgery until mid-February Restricted staff holidays Sir Jeremy Farrar, Scientific Advisory Group for Emergencies https://www.bbc.co.uk/news/live/world-55464932 Reopening schools in January very finely balanced It is going be a trade-off between one or other You cannot have everything. You cannot have the whole of society opening, and schools opening and further education and universities, and keep R below one with this variant A British national disgrace https://www.tagesanzeiger.ch/200-briten-aus-verbier-geflohen-748162397767 https://www.theguardian.com/world/2020/dec/27/hundreds-uk-tourists-flee-covid-quarantine-swiss-ski-resort-verbier Verbier UK to Switzerland flights stopped 20 December Swiss authorities, 21 December Arrivals from UK since 14 December, need to self-isolate for 10 days Swiss authorities tracked down 420 Half missing, geflohen, some later reporting to hotels in France Some rang hotels later to try to get money back 2020 12 Variant Denmark, Germany, Singapore, France, Japan, Spain, Australia, Lebanon, Sweden, Netherlands, Italy, Canada United States CDC trends (Saturday, 28th December) https://covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases Official US hospitalizations https://gis.cdc.gov/grasp/COVIDNet/COVID19_3.html Last reliable data, 21st November Cases, + 152,461 = 18,907,656 Up 7.1% over past 7 days Hospitalizations, 118,720 (22,447) (7,878) Deaths, 324,796 https://covidtracking.com Storm Chaser, Phase 3 Double blind Placebo controlled https://clinicaltrials.gov/ct2/show/NCT04625972 https://www.theguardian.com/world/2020/dec/25/uk-scientists-trial-drug-to-prevent-coronavirus-infection-leading-to-disease AZD7442 monoclonal antibodies Two mAbs to the SARS-CoV-2 S protein RBD Six to 12 months Fc Amino acid substitutions Extend their half-lives Decrease Fc effector function to decrease the potential risk of antibody-dependent enhancement of disease Started 2nd December N = 1,125 people globally Healthcare workers Students in shared accommodation Recently exposed patients Long-term care Military Factory workers Timetable Reports, 4th January Approval, March or April UCLH virologist Dr Catherine Houlihan We know that this antibody combination can neutralise the virus, so we hope to find that giving this treatment via injection can lead to immediate protection against the development of Covid-19 in people who have been exposed Provent trial

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