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Not fully vaccinated, placed in lockdown Introduction https://ourworldindata.org/explorers/coronavirus-data-explorer?tab=map&zoomToSelection=true&facet=none&pickerSort=asc&pickerMetric=location&Metric=Confirmed+cases&Interval=7-day+rolling+average&Relative+to+Population=true&Align+outbreaks=false&country=USA~GBR~CAN~AUS~IRL~NZL Austria https://www.bbc.co.uk/news/world-europe-59283128 Two million, not fully vaccinated, placed in lockdown Spot checks in public spaces (e1,450) Chancellor Alexander Schallenberg We are not taking this step lightly, but unfortunately it is necessary In reality we have told one third of the population: you will not leave your home apart from for certain reasons That is a massive reduction in contacts between the vaccinated and the unvaccinated Initially for 10 days (Children under 12 and recently recovered exempt) Prof Eva Schernhammer, Medical University of Vienna It's already projected that within two weeks we'll have reached the limit Vaccinations x 4 Australia, Queensland Ban on unvaccinated, restaurants, pubs, sports events from 17 December Singapore Unvaccinated, to pay for their own medical bills from December Netherlands Early closing for restaurants and shops, sporting events ONS https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19latestinsights/vaccines Tested positive for COVID-19 antibodies in the week beginning 18 October 2021 (over 18s) 93.1% in England 91.7% in Wales 90.9% in Northern Ireland 92.5% in Scotland Vaccination reduced the risk of testing positive during both the Alpha and Delta period Two doses of Pfizer-BioNTech Reduced the risk of testing positive by, 73% Delta 80% Alpha Two doses of Oxford-AstraZeneca Reduced the risk of testing positive by, 62% Delta 76% Alpha During the Delta period Two doses of either Pfizer-BioNTech or Oxford-AstraZeneca provided a similar level of protection from previous natural infection UK, Health Security Agency Effectiveness of Pfizer and AZ In preventing hospitalisations After the second dose Aged, 16+ Therefore 12 million UK boosters have been given Medical workers, over 50s, higher risk individuals Herd immunity https://www.nature.com/articles/d41586-021-00728-2 https://www.latimes.com/science/story/2021-11-12/cdc-shifts-pandemic-goals-away-from-reaching-herd-immunity 70% 80% 90% Original, alpha then delta Waning immunity Varying social behaviours Breakthrough infections and infectivity Uneven international vaccine roll out Dr Jefferson Jones CDC’s COVID-19 Epidemiology Task Force very complicated We would discourage thinking in terms of a strict goal some kind of threshold where there’ll be no more transmission of infections may not be possible Vaccines, quite effective at preventing severe illness and death, none has proved reliable at blocking transmission of the virus Even if vaccination were universal, the coronavirus would probably continue to spread Dr, Oliver Brooks, CDC Advisory Committee on Immunization Practices Need to increase vaccine uptake Jones’ unexpected admission almost makes you less motivated to get more people vaccinated Dr John Brooks, chief medical officer for the CDC’s COVID-19 response It’s a science-communications problem It’s impossible to predict what herd immunity will be in a new pathogen until you reach herd immunity CDC, redefine success in terms of new infections and deaths

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