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Money for antivirals, $3.2 billion https://www.washingtonpost.com/health/2021/06/17/drugs-for-covid/?utm_campaign=wp_to_your_health&utm Anthony S. Fauci, David Kessler, chief science officer for the covid-19 response Reinvigorate the nation’s antiviral program and test whether existing drugs show promise David Kessler We need this set of tools to close out this pandemic. The hard thing is to recognize with all the success, there’s still several hundred deaths a day. Coronavirus first, then other potential pandemic viruses Pre orders for this pandemic, before they have been shown to work Ann Kwong, virologist, (hepatitis C antiviral) Investors are totally uninterested in antivirals. What they really want is a chronic treatment Nobody ever gets cured of high cholesterol Antivirals, 5 to 10 days Last week, administration committed $1.2 billion 1.7 million doses of molnupiravir (if approved) Merck and Ridgeback Effect of Ivermectin on Anopheles gambiae Mosquitoes Fed on Humans: The Potential of Oral Insecticides in Malaria Control https://academic.oup.com/jid/article/202/1/113/888773 it was licensed for human use and was used in mass drug administration programs to control river blindness; it was administered to more than 80 million adults and children. The drug has proven to be safe. Doses up to 10 times the approved limit are well tolerated by healthy volunteers Adverse reactions are few and usually mild Barcelona Institute for Global Health https://www.isglobal.org/en/healthisglobal/-/custom-blog-portlet/questions-and-answers-about-ivermectin-and-covid-19/2877257/0 More than three billion treatments have been distributed in the context of the Mectizan Donation Program alone With an excellent safety profile. Most adverse reactions are mild, transitory and associated with parasite death rather than with the drug itself. Dr Soumya Swaminathan https://www.ndtv.com/india-news/coronavirus-ivermectin-efficacy-safety-most-important-top-who-scientist-warns-against-ivermectin-use-2439290 Safety and efficacy are important when using any drug for a new indication. WHO recommends against use of 'ivermectin' for COVID-19 except within clinical trials Bram Rochwerg, McMaster University Co-chair, WHO panel that reviewed ivermectin https://www.reuters.com/article/us-health-coronavirus-ivermectin-idUSKBN2BN2HH We certainly need more data in order to make informed decisions We did see an increase in adverse effects in patients that were randomised to ivermectin Repurposed drugs, there can be more harm than any good Merck Statement on Ivermectin use During the COVID-19 Pandemic https://www.merck.com/news/merck-statement-on-ivermectin-use-during-the-covid-19-pandemic/ A concerning lack of safety data in the majority of studies.

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