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Coronavirus (COVID-19) Infection Survey: characteristics of people testing positive for COVID-19 in England, 27 January 2021 https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19infectionsinthecommunityinengland/characteristicsofpeopletestingpositiveforcovid19inengland27january2021 Antigen survey S-gene is no longer detected in the current test Classic symptoms Cough, fever, shortness of breath, loss of taste or loss of smell New UK variant infections Were more likely to report any symptoms Largest difference, more reports of cough, sore throat, fatigue, myalgia, fever More likely to report the classic symptoms Significantly less likely to report loss of taste and smell There is no evidence of difference in the gastrointestinal symptoms, shortness of breath or headaches. UK https://covid.joinzoe.com/data#levels-over-time https://coronavirus.data.gov.uk Cases, + 25,308 = 3,715,054 Hospitalisations, 3,082 = 37,605 (3,961) Deaths, + 1,631 + 1,725 = 101,887 Deaths, + 7,766 = 103,602 Deaths will come down slowly https://www.bbc.co.uk/news/uk-55818636 Prof Chris Whitty a lot more deaths over the next few weeks before the effects of vaccinations kick in Current restrictions just about holding in lowering infection rates Vaccinations First dose, 7,164,387 Second dose, 474,156 Earliest English school return date, 8th March UK travel https://www.bbc.co.uk/news/uk-55821702 Quarantine in hotels, 10 days 30 high risk countries Met at airport transported directly into quarantine South America, South Africa, Portugal travellers already banned Ban on travel for leisure US, CDC data https://covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases Past 7 days https://www.washingtonpost.com/graphics/2020/national/coronavirus-us-cases-deaths/?itid=sf_coronavirus Cases, down 16.4% Deaths, up 10.4% Hospitalizations, down 10.4% Positivity rate, 9.1% Vaccinations 24,391,000 doses given Completed courses, 3,529,000 (1.08%) China Anal swab as a potentially optimal specimen for SARS-CoV-2 detection to evaluate hospital discharge of COVID-19 patients (Future Medicine) https://www.futuremedicine.com/doi/10.2217/fmb-2020-0090 ACE2 is most abundantly expressed on the surface of alveolar epithelial cells and small intestine epithelial cells SARS-CoV-2 shed in the different phases of infection Betacoronavirus genus, can cause respiratory, intestinal, liver and nervous system infections in animals and humans https://www.washingtonpost.com/world/asia_pacific/anal-swab-china-coronavirus/2021/01/27/cc284f56-6054-11eb-a177-7765f29a9524_story.html Recovering patients Continued to test positive days after nasal and throat swabs were negative Quarantine centers Raise rate of identifying infected patients Domestic travel Lunar New Year next month Travelers arriving from overseas Two weeks of hotel quarantine Plus a third week of home quarantine Fourth week of daily reports to health officials EU, Oxford AZ vaccine https://www.bbc.co.uk/news/world-europe-55822602 Not yet approved by EMA August ordered 300 million (+ 100 m) doses Production delays, plants, Netherlands and Belgium Two months behind UK deal signed May 80 million doses expected by March Reduced to 31 million, down 60% for first quarter EU has threatened to restrict vaccine exports EU, Pfizer/BioNTech Order, 600 m doses Delayed supplies for a few weeks Sanofi will help produce 125 million doses in Frankfurt from July Global vaccine tracker https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/ UK vaccine tracker https://coronavirus.data.gov.uk/details/vaccinations US vaccine tracker https://covid.cdc.gov/covid-data-tracker/#vaccinations Europe vaccine tracker https://data.spectator.co.uk/city/vaccines

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