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Most Side Effects Are Not the Drug Failing

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Most side effects are not the drug failing. They are the drug working exactly as designed, and that predictability takes two distinct shapes. Sources FDA. Drugs@FDA Glossary of Terms. https://www.fda.gov/drugs/drug-approvals-and-databases/drugsfda-glossary-terms Marino M, Jamal Z, Zito PM. Pharmacodynamics. StatPearls, 2023. https://www.ncbi.nlm.nih.gov/books/NBK507791/ Kommu S, Carter C, Whitfield P. Adverse Drug Reactions. StatPearls, 2024. https://www.ncbi.nlm.nih.gov/books/NBK599521/ Ngo VTH, Bajaj T. Ibuprofen. StatPearls, 2024. https://www.ncbi.nlm.nih.gov/books/NBK542299/ Kelleher KJ et al. Pharos 2023: an integrated resource for the understudied human proteome. Nucleic Acids Research 2023;51(D1):D1405-D1416. https://doi.org/10.1093/nar/gkac1033 https://pharos.nih.gov/

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