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CDC, Friday 18th June, Review potential link between heart inflammation and mRNA vaccines https://www.medscape.com/viewarticle/952905?src=wnl_edit_tpal&uac=127834AR&impID=3435883&faf=1 https://www.cdc.gov/vaccines/acip/meetings/downloads/agenda-archive/agenda-2021-06-18-508.pdf COVID-19 mRNA vaccines in adolescents and young adults: benefit-risk discussion Discussion CDC’s Advisory Committee on Immunization Practices CDC, identified 216 cases of heart inflammation after 1st dose Another 573 cases after the second shot 172 million people, at least one shot (789) One in 217, 997 https://www.fda.gov/media/150054/download Under 30 years, n = 475 285 with known disposition 15 still in hospital 3 ICU 270 discharged 180 (81%) full recovery 41 (19%) ongoing signs or unknown status Myocarditis in over 12s Presence of one, new or worsening Chest pain pressure discomfort Dyspnea SOB pain with breathing Palpitations ECG changes Troponins Abnormal cardiac function Pericarditis Acute chest pain Pericardial rub New ST elevation or PR depression New or worsening pericardial effusion CDC safety expert Tom Shimabukuro We’re still learning about the rates of myocarditis and pericarditis As we gather more information we’ll begin to get a better idea of the post-vaccination rates and hopefully be able to get more detailed information by age group Mr Biden https://www.bbc.co.uk/news/uk-57436535 Confirmed 500 million doses of Pfizer 92 low and middle-income countries and the African Union Manufactured from August Mr Biden The United States is providing these half billion doses with no strings attached. Our vaccine donations don't include pressure for favours, or potential concessions. We're doing this to save lives. G 7s another 500 million UK, 100 million Five million doses by the end of September 25 million more by the end of the year Federal regulators Johnson & Johnson vaccine by six weeks, up to 4.5 months https://www.washingtonpost.com/health/2021/06/11/fda-releases-johnson-johnson-vaccine-from-emergent-plant/ 60 million doses to be discarded South Africa implications Chile Population 19 million https://www.washingtonpost.com/nation/2021/06/11/coronavirus-covid-live-updates-us/ Santiago going into full lockdown from tomorrow Fully vaccinated, 58% At least one dose, 75% Cases, + 7,700 Hospitals crowded ICU at 98% Jose Luis Espinoza, Chile’s National Federation of Nursing Associations Members were on the verge of collapse Chinese-made CoronaVac vaccine 20 million vaccine doses administered 15.8 million, CoronaVac vaccine 3.6 million Pfizer-BioNTech A few Oxford-AstraZeneca Health Ministry, Wednesday and Thursday, 27% of cases were in fully vaccinated 74% under the age of 49 April, University of Chile CoronaVac, 56% effective two weeks after second dose Pandemic fatigue, travel, variants https://www.nature.com/articles/d41586-021-01497-8 The World Health Organization (1st June) approved CoronaVac at 51% effective at preventing COVID-19 (in late-stage trials) https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3822780 HCWs in Brazil 100% effective at preventing severe disease and death 600 million doses have been delivered (Sinopharm, efficacy of 79% against symptomatic disease) PHE Delta viral assessment https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/992981/10_June_2021_Risk_assessment_for_SARS-CoV-2_variant_DELTA.pdf
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