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Vitamin D and pandemic science

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Explore Vitamin D and pandemic science with 295,010 views, 7,588 likes, and 2,216 comments. Experience the impact of this video content that has captured audience attention.

US, NHI Guidelines https://ods.od.nih.gov/factsheets/VitaminD-Consumer/ https://www.healthline.com/nutrition/how-much-vitamin-d-to-take#How-Common-Is-Vitamin-D-Deficiency About 42% of the US population is vitamin D deficient 82% in black people 70% in Hispanics Public health England https://www.gov.uk/government/news/phe-publishes-new-advice-on-vitamin-d Vitamin D dose IU mcg 400 10mcg 800 20mcg 1,000 25mcg 2,000 50mcg 4,000 100mcg 6,000 150 mcg Facial Masking for Covid-19 — Potential for “Variolation” as We Await a Vaccine (NEJM, 14th September) https://www.nejm.org/doi/full/10.1056/NEJMp2026913 https://www.nejm.org/doi/pdf/10.1056/NEJMp2026913?articleTools=true Universal mask wearing might make mild or asymptomatic disease more likely A form of “variolation” Inoculation Generate immunity and thereby slow the spread of the virus Viral shedding from the noses and mouths of patients, presymptomatic or asymptomatic Shedding rates equivalent to those among symptomatic patients SARS -1 A strong relationship between public masking and pandemic control SARS - CoV - 2 Recent virologic, epidemiologic, and ecologic data Hypothesis that facial masking may also reduce the severity of disease among people who do become infected Long-standing theory of viral pathogenesis Severity of disease is proportionate to the viral inoculum received Typical rate of asymptomatic infection, estimated to be 40% by the CDC in mid-July, Settings with universal facial masking, 80% Also less severe and less deaths Tiny Antibody Component Highly Effective Against COVID-19 https://www.upmc.com/media/news/091420-mellors-dimitrov-covid-ab8 Ab8 evidence of efficacy in vitro and animals Monoclonal antibodies to begin UK trial https://www.bbc.co.uk/news/health-54120753 n = 2,000 2,000 more needed (me) UK Recovery Trial Neutralising antibodies REGN-COV2 will be a new arm of the trial Mixture of two monoclonal antibodies US biotech company Regeneron Regeneron, monoclonal antibodies, Ebola Both attach to the spike of the virus at slightly different places PFIZER/BIONTECH VACCINE Albert Bourla, (CEO of Pfizer) https://www.dailymail.co.uk/news/article-8729507/Pfizer-CEO-says-coronavirus-vaccine-distributed-Americans-end-October.html Making good progress with a COVID vaccine 60 per cent chance, will know by the end of October their vaccine was effective and safe Trials have been carried out on 30,000 people, and that is expanding to 44,000 Then move on to FDA to certify Already had 'hundreds of thousands' of doses ready to go Mass manufacture in hand UAE approves urgent use of China-developed COVID-19 vaccine after test on 31,000 volunteers Phase I and II results June 100 percent of volunteers generating antibodies after two doses in 28 days https://www.globaltimes.cn/content/1200995.shtml 6 weeks, 31,000 volunteers, 125 nationalities, phase 3 started 16th July United Arab Emirates (UAE) emergency approval for use China National Pharmaceutical Group (Sinopharm) Department of Health of Abu Dhabi Clinical trials, simultaneous in Bahrain, Jordan and Egypt 100,000 injections given so far, no adverse reactions, no infections Mild and expected side effects No severe side effects or complications Volunteers, 1,000, chronic diseases Volunteers now receiving their second shot AI and supercomputing, trial results, fast India May fast track vaccine https://www.telegraph.co.uk/global-health/science-and-disease/india-considers-fast-tracking-covid-19-vaccine-vulnerable-groups/

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