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Explore COVID-19 and Zinc with 1,970,417 views, 40,760 likes, and 6,229 comments. Experience the impact of this video content that has captured audience attention.

President Trump taking zinc (WSJ) https://www.wsj.com/articles/trump-takes-zinc-maybe-you-should-too-11601916665 Low zinc levels at clinical admission associates with poor outcomes in COVID-19, (11th October) https://www.medrxiv.org/content/10.1101/2020.10.07.20208645v1 Zinc balances immune responses and also has a proven direct antiviral action against some viruses. Zinc deficiency (ZD) is a common condition in elderly and individuals with chronic diseases Increased intracellular zinc concentrations efficiently impair replication Resulting in a lower number of viruses Retrospective analysis Patients admitted in Barcelona 15th March to 30th April 2020 Clinical severity of COVID-19 and PMH assessed Fasting plasma zinc levels measured routinely at admission N = 611 Mean age, 63 years Male 332, (55%) Total mortality was 87 patients (14%) during study time But 249 of 611 patients studied Of the 249, 21 (8%) died Baseline zinc levels Died, (21 people) mean plasma zinc = 43 μg/dl Survived, (228 people) mean plasma zinc = 63.1 μg/dl Higher zinc levels, associated with lower maximum levels of interleukin-6 during the period of active infection Zinc level lower than 50 μg/dl at admission, 2.3 times increased risk of in-hospital death Compared with those of 50 μg/dl or higher Lower zinc levels at admission correlate with higher inflammation in the course of infection and poorer outcome Low plasma zinc levels at admission are associated with mortality in COVID-19 in our study Further studies are needed to assess the therapeutic impact of this association COVID-19: Poor outcomes in patients with zinc deficiency (International Journal of Infectious Diseases, November 2020) Chennai, India Prospective study of fasting zinc levels in COVID-19 patients at the time of hospitalization Healthy controls median 105.8 μg/dl https://www.sciencedirect.com/science/article/pii/S120197122030730X Zinc is a trace element with potent immunoregulatory and antiviral properties Is utilized in the treatment of coronavirus disease 2019 (COVID-19) Patients with serious COVID-19 had significantly low zinc levels in comparison to healthy controls Zinc deficient COVID patients developed more complications Zinc deficient patients 70.4% developed complications Non zinc deficient patients, 30.0% developed complications, (p = 0.009) Acute respiratory distress syndrome More need of steroids Increased mortality Zinc deficient COVID patients had a prolonged hospital stay Zinc deficient patients, 7.9 days Non zinc deficient patients, 5.7 days, (p = 0.048) In vitro studies Reduced zinc levels increase SARS-CoV-2 virus receptor interactions Increased zinc levels inhibit ACE2 expression https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/ What zinc does Catalytic activity of approximately 100 enzymes Plays a role in immune function Protein synthesis Wound healing DNA synthesis Cell division Normal growth and development, pregnancy, childhood, adolescence Required for sense of taste and smell Zinc and immunity Severe zinc deficiency depresses immune function Even mild to moderate degrees of zinc deficiency can impair macrophage and neutrophil functions, natural killer cell activity, and complement activity Body requires zinc to develop and activate T-lymphocytes Low zinc levels have shown reduced lymphocyte proliferation …. that can be corrected by zinc supplementation Low zinc status has been associated with increased susceptibility to pneumonia and other infections in children in developing countries and the elderly Foods Oysters Sea food Beef Pork Baked beans Fortified cereals Pumpkin seeds Yogurt Cashew nuts Chickpeas Oats Almonds Vitamin D and zinc can be made in bulk for essentially nothing

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