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Black fungus India, cases, 9,000 https://www.bbc.co.uk/news/world-asia-india-57217246 Mortality rate, 50% Most cases 12 to 18 days after CoViD recovery Gujarat and Maharashtra and 15 more states (All 29 states have been told to declare an epidemic) Maharaja Yeshwantrao Hospital, Indore Last week, 8 patients Last weekend, 185 patients More than 80% need surgery immediately Hospital has set up 11 wards, 200 beds to treat black fungus (400 sufferers in Indore) Dr VP Pandey This surge in patients was definitely unexpected We used to see one or two cases a year previously The black fungus infection has now become more challenging than Covid-19 If patients are not treated in time and properly, than the mortality rate can go up to 94% The cost of treatment is expensive, and the drugs are in short supply Amphotericin B or "ampho-B" anti-fungal intravenous injection Every day for up to eight weeks Majority of the patients had recovered from Covid-19 and were male Most had been treated with steroids, all had underlying conditions, mainly diabetes A separate study 100 cases of Covid-19 patients who contracted Mucormycosis 79 were men 83 were diabetic Dr Akshay Nayar, eye surgeon No patient of mucormycosis has normal blood sugar Caused by exposure to mucor mould Commonly found in soil, plants, manure, decaying fruits and vegetables Ubiquitous, found in soil and air and even in the nose and mucus of healthy people Sinuses, brain, lungs Pfizer and AstraZeneca jabs effective against Indian variant (PHE) https://khub.net/documents/135939561/430986542/Effectiveness+of+COVID-19+vaccines+against+the+B.1.617.2+variant.pdf/204c11a4-e02e-11f2-db19-b3664107ac42 https://www.gov.uk/government/news/vaccines-highly-effective-against-b-1-617-2-variant-after-2-doses The B.1.617.2 COVID-19 variant First detected in India in December 2020 Most commonly variant in India from mid-April 2021 Now detected, 43 countries We estimate the effectiveness of the BNT162b2 and ChAdOx1 COVID-19 vaccines against symptomatic disease Data on all symptomatic sequenced cases of COVID-19 in England was used Compared to vaccination status 12,675 sequenced cases 11,621 had B.1.1.7 1,054 had B.1.617.2 Results for both vaccines were similar after one dose B.1.617.2, 33.5% B.1.1.7, 51.1% Results after 2 doses of BNT162b2 Pfizer B.1.1.7, 93.4% B.1.617.2, 87.9% Results after 2 doses of ChAdOx1 Oxford AZ B.1.1.7, 66.1% B.1.617.2, 59.8% Interpretation These findings suggest a modest reduction in vaccine effectiveness A clear increase in levels of effectiveness after two doses Rollout of second doses of ChAdOx1 was later than BNT162b2 Oxford AZ effectiveness probably increases beyond two weeks after second dose Numbers of cases and follow-up periods are currently insufficient to estimate effectiveness against severe disease, including hospitalisation and mortality Previous vaccine effectiveness estimates with other variants have shown higher levels of effectiveness against more severe outcomes Therefore, higher levels of effectiveness against severe disease may be anticipated with the B.1.617.2 vaccine. Matt Hancock This new evidence is groundbreaking – and proves just how valuable our COVID-19 vaccination programme is in protecting the people we love. Dr Mary Ramsay, Head of Immunisation at PHE This study provides reassurance that 2 doses of either vaccine offer high levels of protection against symptomatic disease from the B.1.617.2 variant. We expect the vaccines to be even more effective at preventing hospitalisation and death, so it is vital to get both doses to gain maximum protection against all existing and emerging variants. Nadhim Zahawi with 13,000 lives saved and 39,100 hospitalisations prevented overall Today’s data is astounding and a true reflection of just how important it is to get both your jabs when offered.

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