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Kwashiorkor and marasmus - USMLE Biochemistry

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๐Ÿ“Œ ๐…๐จ๐ฅ๐ฅ๐จ๐ฐ ๐จ๐ง ๐ˆ๐ง๐ฌ๐ญ๐š๐ ๐ซ๐š๐ฆ:- https://www.instagram.com/drgbhanuprakash ๐Ÿ“Œ๐—๐—ผ๐—ถ๐—ป ๐—ข๐˜‚๐—ฟ ๐—ง๐—ฒ๐—น๐—ฒ๐—ด๐—ฟ๐—ฎ๐—บ ๐—–๐—ต๐—ฎ๐—ป๐—ป๐—ฒ๐—น ๐—›๐—ฒ๐—ฟ๐—ฒ:- https://t.me/bhanuprakashdr ๐Ÿ“Œ๐—ฆ๐˜‚๐—ฏ๐˜€๐—ฐ๐—ฟ๐—ถ๐—ฏ๐—ฒ ๐—ง๐—ผ ๐— ๐˜† ๐— ๐—ฎ๐—ถ๐—น๐—ถ๐—ป๐—ด ๐—Ÿ๐—ถ๐˜€๐˜:- https://linktr.ee/DrGBhanuprakash Kwashiorkor and marasmus are two separate diseases, but the former is so often superimposed on the latter that most clinical cases of kwashiorkor are better characterized as "marasmic kwashiorkor." Kwashiorkor is a disease syndrome resulting from a severe deficiency of dietary protein relative to caloric intake. It is characterized typically by retardation of growth and development, edema, fatty enlarged liver, anorexia, and alterations in the color and texture of the hair and the skin. The child is severely apathetic, and at the same time, irritable. Pneumonia and diarrhea are almost always present. Kwashiorkor occurs in young children because at this period of life, protein requirements per kilo of body weight are relatively high, diets are more likely to be deficient in protein, and complicating infections that increase the need for protein are most common. The name kwashiorkor comes from the Ga language of Ghana and means literally "first-second," i.e. the disease of the first child when it is displaced at the mother's breast. It has had many other names in different parts of the world, but the name kwashiorkor, given in its original description, is now universally accepted. In the early 20th century, a form of kwashiorkor given the name mehlnahrschaden (starch dystrophy) was described in Europe in infants fed excessive starch and little else. Cases have been reported in Jamaica in children with a history of excessive calories from cassava starch and very little dietary protein. Kwashiorkor has been observed in older children and adults, but only rarely. Inadequate dietary intake of protein is always part of the history. A deficient intake of some micronutrients is common, and this contributes to clinical variations among individuals and geographic regions. Caloric intake is also usually low, and accounts for the #marasmus, on which #kwashiorkor is commonly superimposed, as a result of the adverse metabolic effects of infection on protein nutrition. These effects include anorexia (which causes a further decrease in protein intake) and an increase in the catabolic loss of nitrogen in the urine. In addition, diarrhea may reduce nitrogen adsorption from the gastrointestinal tract. #usmlevideos #pathologyvideos #animatedpathovideos #animatedmedicalvideos #drgbhanuprakash #usmlestep1videos #neetpg #fmge

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