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Protein Berbahaya yang Bisa Bunuh Manusia

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Beberapa puluh tahun lalu, banyak orang suku Fore di Papua Nugini meninggal secara misterius. Sebelumnya, mereka kena penyakit yang bikin penderitanya susah jalan, bergerak tanpa sadar, hilang ingatan, bahkan sampe kesulitan makan. Setelah ditelusurin, ternyata penyebabnya adalah… ritual makan otak manusia yang masih dilakuin suku Fore kala itu. Ya, ternyata pelakunya ada di dalam otak manusia yang dimakan. Suatu zat protein yang abnormal. Oke, protein apa ini sebenarnya? Kenapa bukannya bikin sehat, malah jadi penyakit? Enjoy the video! --- Tanyakan pertanyaan aneh anda di sini! NGGA ada pertanyaan yang bodoh! 'Kok Bisa' ngga cuma sekedar mencoba menjawab pertanyaan-pertanyaan yang terlihat bodoh, aneh dan dungu di sini, tapi juga mencoba menumbuhkan rasa keingintahuan anda terhadap segala hal di dunia ini. Jadi, tunggu apalagi? Ayo subscribe, let's watch the videos and go curiosity! --- FAQ (Frequently Asked Questions): Q: Min, upload tiap hari apa? A: Tiap hari Rabu dan Sabtu. Tapi kadang-kadang ada video yang butuh waktu pembuatan lebih lama. So, stay tuned! Q: Min, animasinya pake software apa? A: Adobe after effects Q: MIN, KENAPA DI VIDEONYA ADA BAKSONYA TERUS!? A: Bakso is inspiration *wink --- Follow our social media for more updates, stuff and facts! Instagram: https://instagram.com/kokbisa Twitter: https://twitter.com/kokbisachannel Facebook: https://www.facebook.com/kokbisachannel Line: http://bit.ly/linekokbisa --- For business inquiries: [email protected] --- References: Alpers, M. P. (2008). The epidemiology of kuru: monitoring the epidemic from its peak to its end. Philosophical Transactions of the Royal Society B, 363(1510), 3707–3713. https://doi.org/10.1098/rstb.2008.0071 Bartee, L. (n.d.). The production of a protein. Pressbooks. https://openoregon.pressbooks.pub/mhccmajorsbio/chapter/production-of-a-protein/# Das, A. S., & Zou, W. (2016). Prions: Beyond a single protein. Clinical Microbiology Reviews, 29(3), 633–658. https://doi.org/10.1128/cmr.00046-15 Facts about variant Creutzfeldt-Jakob disease. (2017, June 26). European Centre for Disease Prevention and Control. https://www.ecdc.europa.eu/en/vcjd/facts Frazer, J. (2018, April 9). Prions are forever. Scientific American Blog Network. https://blogs.scientificamerican.com/artful-amoeba/prions-are-forever/ Human Transmissible Spongiform Encephalopathies (TSEs) - MN Dept. of Health. (n.d.). https://www.health.state.mn.us/diseases/tses/human.html Klimova, N., Makarava, N., & Baskakov, I. V. (2015). The diversity and relationship of prion protein self-replicating states. Virus Research, 207, 113–119. https://doi.org/10.1016/j.virusres.2014.10.002 Mabbott, N. A., Bradford, B., Pal, R., Young, R., & Donaldson, D. S. (2020). The effects of immune system modulation on Prion disease susceptibility and pathogenesis. International Journal of Molecular Sciences, 21(19), 7299. https://doi.org/10.3390/ijms21197299 Prion Diseases | CDC. (n.d.). https://www.cdc.gov/prions/index.html Prion diseases. (2021, August 8). Johns Hopkins Medicine. https://www.hopkinsmedicine.org/health/conditions-and-diseases/prion-diseases Prion Diseases | Brain Institute | OHSU. (n.d.). https://www.ohsu.edu/brain-institute/prion-diseases Prions, prion diseases and decontamination. (2003, October 1). PubMed. https://pubmed.ncbi.nlm.nih.gov/14981553/ What are prions? (2013, November 26). https://www.prionalliance.org/2013/11/26/what-are-prions/ Wadsworth, J., Joiner, S., Linehan, J. M., Asante, E. A., Brandner, S., & Collinge, J. (2008). The origin of the prion agent of kuru: molecular and biological strain typing. Philosophical Transactions of the Royal Society B, 363(1510), 3747–3753. https://doi.org/10.1098/rstb.2008.0069 Watson, N. V., Brandel, J., Green, A., Hermann, P., Ladogana, A., Lindsay, T., Mackenzie, J. B. D., Pocchiari, M., Smith, C., Zerr, I., & Pal, S. (2021). The importance of ongoing international surveillance for Creutzfeldt–Jakob disease. Nature Reviews Neurology, 17(6), 362–379. https://doi.org/10.1038/s41582-021-00488-7 Website. (2023, April 13). Treatment. nhs.uk. https://www.nhs.uk/conditions/creutzfeldt-jakob-disease-cjd/treatment/ --- Credits: - Kevin MacLeod for awesome music - Tiffani Angelica, for this episode's end narrator (instagram.com/tiffaniangelica) - And a massive THANK YOU to everyone for watching this and for all of your support!

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