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In this interview from theCUBE + NYSE Wired: MedTech Unplugged, Richard Yang, chief executive officer of Sonablate, joins theCUBE + NYSE Wired's Gemma Allen to discuss how focused ultrasound is turning sound waves into a precision surgical tool. Yang explains how high-intensity focused ultrasound (HIFU) treats prostate cancer and BPH without incisions, targeting only the tissue that matters while preserving sexual function and continence. He details how a device delivered through the rectal wall achieves disease control comparable to prostatectomy or radiation over 10 to 15 years, backed by data from over 70,000 patients worldwide and 200 peer-reviewed publications, with patients returning home the same day. The conversation also touches on the grueling, decades-long path required to prove out a pioneering medical device, from animal studies through years of clinical follow-up before outcomes can be trusted. Yang breaks down how AI is already enhancing the platform through tools like Tissue Change Monitoring, which analyzes imaging in real time to flag under-treated tissue and guide energy adjustments, rather than replacing physician judgment. He outlines Sonablate's ambition to expand beyond urology into neuromodulation for stroke, Parkinson's and Alzheimer's, as well as soft tissue diseases, pain management and immunotherapy applications. From winning over skeptical surgeons to preparing for a planned IPO in 2027 or early 2028 alongside a $200 million pre-IPO raise, Yang lays out how Sonablate intends to scale its "treat what matters" mission across dozens of new disease areas. Find more SiliconANGLE news and analysis https://siliconangle.com/ Follow theCUBE's wall-to-wall event coverage https://siliconangle.com/events/ Learn about the latest theCUBE events https://www.thecube.net/ 00:00 - Revolutionizing Surgery: The Sonablate HIFU Journey 02:21 - Prostate Cancer Treatment and Side Effects 04:41 - From Innovation to Implementation: Navigating the MedTech Journey 06:56 - Role of AI in Medical Devices 08:57 - Advancing Sonablate: Applications and Market Strategies 15:27 - Charting the Path Ahead: Future Plans and Final Thoughts #theCUBE #MedTechUnplugged #theCUBEresearch #NYSEWired #Sonablate #MedTech #PrecisionMedicine

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