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Diabetes morbidity, India, 77 million, China, 116 million, UK, 3.9million, US 34 million In case you want to support Our community outreach through donations USE SENDWAVE/ WorldRemit /Western Union Mobile money number:+256785698803 Country: Uganda Registered name : Wefwafwa Andrew Email me when you send: [email protected] Addresses: Republic street City: Mbale city Country: Uganda UK 3.9 to 4.7 million, + 700 new cases per day https://www.diabetes.org.uk/about_us/news/new-stats-people-living-with-diabetes US, 34.2 million https://www.cdc.gov/diabetes/library/features/diabetes-stat-report.html Rhino-orbital mucormycosis following COVID-19 in previously non-diabetic, immunocompetent patients https://www.tandfonline.com/doi/abs/10.1080/01676830.2021.1960382?journalCode=iorb20 India, more than 45,000 cases of Mucormycosis Affects nose, eyes and sometimes the brain Usual onset, 12-18 days after recovery from Covid-19 13 of 127 patients had new onset diabetes Average age, 36 years Seven of 13, not given steroids or supplemental oxygen Covid-19: Fears over sharp rise in diabetes in India https://www.bbc.co.uk/news/world-asia-india-58066767 https://www.sciencedirect.com/journal/diabetes-and-metabolic-syndrome-clinical-research-and-reviews Dr Anoop Misra Our assessment is that such patients were probably predisposed to diabetes because of obesity and family history Severe diabetes caused by pancreatic damage, less common Proportion of newly diagnosed diabetes in COVID-19 patients: A systematic review and meta-analysis https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14269 https://www.washingtonpost.com/health/2021/02/01/covid-new-onset-diabetes/ Meta-analysis, 8 studies, n = 3,700 patients 14.4% for newly diagnosed diabetes in hospitalized COVID-19 patients newly diagnosed diabetes may confer a greater risk for poor prognosis We are now seeing a classic example of a lethal intersection between a communicable and a non-communicable disease. Physiology Stress response associated with severe illness Treatment with glucocorticoids Diabetogenic effect of COVID-19 should also be considered High degree of insulin resistance High insulin requirements in severely or critically ill COVID-19 patients with diabetes More diabetic ketoacidosis and hyperosmolar hyperglycaemic in COVID-19 patients with diabetes SARS-CoV-2), attaching to ACE2 receptors in beta cells May also injure beta cells by pro-inflammatory cytokines (e.g. interleukin-6) Enhancing autoimmunity in genetically predisposed people ACE2 receptors are expressed in the liver, adipose tissue and skeletal muscle May impair responses to insulin Exploring research: can coronavirus cause diabetes, or make it worse? https://www.diabetes.org.uk/about_us/news/new-worse-cases-coronavirus#:~:text=Small%20studies%20looking%20at%20pancreas,can't%20produce%20enough%20insulin. https://care.diabetesjournals.org/content/early/2020/08/13/dc20-1551 47,000 people in England, admitted to hospital for coronavirus before August 2020 Seven months after discharged 5% of people went on to develop diabetes Hospitalised patients, 1.5 times more likely to be diagnosed with diabetes after discharge Matched with non- hospitalised people of the same age and background Lets find out http://covidiab.e-dendrite.com Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study https://pubmed.ncbi.nlm.nih.gov/33789877/ Follow-up of 140 days, 47,780 admissions 14,060 of readmitted (x4) 5,875 died after discharge (x8) Also increased Respiratory disease (P 0.001) Diabetes (P 0.001) Cardiovascular disease (P 0.001) Increased rates of multiorgan dysfunction

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