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Burden and characteristics of COVID-19 in the United States during 2020 Columbia University and NIH, Director Francis S. Collins, Nature https://pubmed.ncbi.nlm.nih.gov/34438440/#affiliation-3 United States, 2020, highest numbers of reported cases and deaths In the light of later antibody studies March 11.3% December, 24.5% Population susceptibility at year's end was 69.0% So, 31% of population had been exposed (100 million people) Prevalence rates rose above 0.8% by end of 2020 As high as 2.4% in some major metropolitan areas Infection fatality rate fell to 0.3% by end of 2020 https://www.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/children-and-covid-19-state-level-data-report/ As of September 2 5,049,465 children have tested positive 252,000 cases were added the past week Largest number of child cases in a week ever Since the pandemic began, children, 15.1% of total cumulated cases Week ending September 2nd, 26.8% of reported weekly COVID-19 cases 2,400 children were hospitalized nationwide (highest in pandemic) Hospitalizations (24 states and NYC reported) Children ranged from 1.6%-4.1% of total cumulated hospitalizations 0.1%-1.9% of all their child COVID-19 cases resulted in hospitalization Mortality (45 states) Children were 0.00%-0.27% of all COVID-19 deaths (7 states reported zero child deaths) 0.00%-0.03% of all child COVID-19 cases resulted in death Vaccination in children Half of children ages 12 to 15 have received at least one vaccine dose 58 percent for 16- and 17-year-olds Anthony Fauci, National Institute of Allergy and Infectious Diseases We’ve got to get the school system masked, in addition to surrounding the children with vaccinated people That’s the solution Los Angeles mandates today Soon mandate vaccination for school attendance 600,000 would have to get their first shot by Oct. 3 Second shot by the end of October (LA counts since last month) Direct link to vote, https://www.youtube.com/c/Campbellteaching/community Pascal Soriot, AstraZeneca chief executive on Booster doses https://www.telegraph.co.uk/business/2021/09/07/covid-booster-jab-campaign-may-not-needed-says-astra-boss/ UK is still "a few weeks away" from being able to decide Moving too quickly to boost across the entire adult population will deprive us of these insights, leaving this important decision to rest on limited data NHS resource implications Nadhim Zahawi NHS is ‘ready to go’ Philip Dormitzer, Pfizer’s chief scientific officer Encouraged booster shots Dismissed criticism that his company should have produced a more potent vaccine Professor Sarah Gilbert https://inews.co.uk/news/politics/creator-oxford-vaccine-sarah-gilbert-warns-vulnerable-will-have-shield-covid-19-cases-rise-1096315 UK, 3.8 million people classed as clinically extremely vulnerable In people who have been vaccinated and have had the two doses, they will be well protected against disease that is severe enough to put them in hospital and against death And there are unfortunately some people with particular health conditions that mean they just don’t respond to a vaccine and they are going to have to make sure that they are protected, probably by shielding again, if there is a lot of spread of the virus https://www.gov.uk/government/publications/guidance-on-shielding-and-protecting-extremely-vulnerable-persons-from-covid-19/guidance-on-shielding-and-protecting-extremely-vulnerable-persons-from-covid-19 we are advising clinically extremely vulnerable people, as a minimum, to follow the same guidance as everyone else you may wish to think particularly carefully about additional precautions you might wish to continue to take Sweden Removing all remaining restrictions by the end of this month Vietnam Health Ministry, offering Pfizer-BioNTech as a second-dose after Moderna (low supplies of the Moderna) Switzerland Covid certificates for bars, restaurants, fitness centres starting Monday (Hospitals busy with wave of infections) Proof of vaccination, recovery from infection or negative test result Novavax Started early-stage study to test combined flu and booster coronavirus vaccine Along with an adjuvant

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