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Inflammatory Syndrome in Children

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Cases of this severe disease in children are very low in omicron times Original video for solar lights, https://www.youtube.com/watch?v=dY-IatTFJGM&t=150s Wefwafwa's channel, please subscribe to help support this work, https://www.youtube.com/channel/UCzsLklGgOttU3Se-WGLp7ow E mail for Wefwafwa [email protected] Please e mail Wefwafwa if you would like to be involved in this community health project MIS-C COVID Overall cases in children this year, 4.6 million Multisystem Inflammatory Syndrome What is MIS? MIS is a rare but serious condition associated with COVID-19 in which different body parts become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs. https://amp.cnn.com/cnn/2022/02/22/health/mis-c-omicron-waiting-for-trouble/index.html https://covid.cdc.gov/covid-data-tracker/#mis-national-surveillance Total MIS-C cases, 6,851 Deaths, 59 Child cases, 12.5 million since start of pandemic Children, 0.00%-0.25% of all COVID-19 deaths https://www.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/children-and-covid-19-state-level-data-report/ The median age 9 years Half of children with MIS-C were between the ages of 5 and 13 years. 60% of reported patients were male. 59% of the reported patients Hispanic/Latino or black Black, 2,050 Hispanic/Latino, 1,746 98% of patients had a positive test result for SARS CoV-2 2% of patients had contact with someone with COVID-19 MIS-C can occur weeks after COVID-19 and even if the child or family did not know the child had COVID-19. Clinical Criteria Fever, ≥38.0 C) for ≥24 hours Shock or hypotension Severe cardiac illness myocarditis, pericarditis, coronary artery dilatation/aneurysm new-onset right or left ventricular dysfunction 2nd/3rd degree A-V block ventricular tachycardia Rash AND non-purulent conjunctivitis New-onset neurologic signs and symptoms Encephalopathy, seizures, meningeal signs, or peripheral neuropathy (including Guillain-Barré syndrome) Abdominal pain, vomiting, or diarrhea Thrombocytopenia Elevated inflammatory markers A positive SARS-CoV-2 test for current or recent infection by RT-PCR, serology, or antigen detection Dr. Roberta DeBiasi, Infectious Disease Division chief at Children's National Hospital, Washington, DC It always follows the same pattern It's always two to six weeks after we see the spike from whatever variant it is, and then we're on the lookout for MIS-C. And then, sure enough, it comes." some of the MIS-C patients have been vaccinated, but the vast majority are not we thought we may see an uptick with Omicron, but we haven't. University of Pittsburgh Medical Center, Dr. Marian Michaels Luckily, in our area we are not seeing a surge I'm very grateful Seattle Children's Dr. Michael Portman, director of research in the Division of Cardiology More MIS-C cases since mid-December 2021 https://www.ahajournals.org/doi/10.1161/JAHA.121.023251 most children with MIS-C begin recovering in the first week after hospital discharge and fully recover heart function within three months

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