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Pandemic Update, 30 September

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Correction, Number of infections in India is proabably 9, 620,000, not 60, million as written. However the IFR calculation is still valid as this is based on the number of reported deaths, compared to the overall population. This means the US is likly to have a higher overall number of infections, compared to India. North Korea https://www.theguardian.com/world/live/2020/sep/29/coronavirus-live-news-rapid-covid-19-tests-to-be-rolled-out-worldwide-as-global-deaths-near-one-million Coronavirus under safe and stable control, (NK UN ambassador, Kim Song) Thanks to the far-sighted leadership of the government of the DPRK ... the anti-epidemic situation in our country is now under safe and stable control UK Cases, 6,874 + 6,042 + 5,693 + 4,044 + 7,143 Highest single figure for 24 hours Cases, 19, 247 + 19, 661 + 19, 523 + 19,373 + Active cases, Deaths, +71 Highest 24 hours since July India Cases, 6, 148, 562 Deaths, 96, 318 Indian Council of Medical Research https://www.hindustantimes.com/india-news/icmr-publishes-first-sero-survey-results-6-4-million-were-likely-covid-19-infected-around-may/story-FAKW5iR14gZ4OgFqa8f8xN.html National antibody study 30,283 households and 28,000 individuals National prevalence, 0.74% 60 million infections 18 – 45 years (43.3%) 46 – 60 years (39.5%) IFR = 0.16% Deaths at 70% of population infected would be 1, 456, 000 France Cases, + 4,070 (Mon) + 8,051 (Tue) Deaths, 81 + 85 Hospitalised, + 85 = 6,500 ITU, + 40 = 1,204 US Recent Increase in COVID-19 Cases Reported Among Adults Aged 18–22 Years — United States, May 31–September 5, 2020 https://www.cdc.gov/mmwr/volumes/69/wr/mm6939e4.htm?s—cid=mm6939e4—w Young adults with COVID-19 can spread infection to their contacts and communities. August 2–September 5 Weekly cases, 18–22 years Increased 55% nationally Northeast (144%) Midwest (123%) Increases in cases not attributable to increased testing. Therefore Young adults, also in colleges and universities Should take precautions Mask wearing, social distancing, and hand hygiene, and follow local, state, and federal guidance Institutions of higher education should take action to promote healthy environments Multiple COVID-19 Clusters on a University Campus — North Carolina, August 2020 https://www.cdc.gov/mmwr/volumes/69/wr/mm6939e3.htm?s_cid=mm6939e3_w A North Carolina university Rapid increase in cases and clusters within 2 weeks of opening August 3–25 670 laboratory-confirmed cases 96% were among patients aged less than 22 years Eighteen clusters of five or more epidemiologically linked cases All within 14 days of one another Student gatherings and congregate living settings Both on and off campus contributed Therefore Enhanced measures are needed to reduce transmission at institutes of higher education Reducing on-campus housing density Ensuring adherence to masking and other mitigation strategies Increasing testing Discouraging student gatherings. Vaccine https://www.dw.com/en/coronavirus-vaccine-why-does-indias-serum-institute-have-a-head-start/a-55089750 Pune, Serum Institute of India World's largest manufacturer of vaccines, 1.5 billion vaccine doses annually Mostly for the developing world. Polio, diphtheria, tetanus, pertussis, Hib, Hepatitis B, measles and rubella Covishield, Oxford / AstraZeneca 2 million does so far Increasing to 10 million per month 100 million if required Stage III clinical trials, Brazil, South Africa €12 ($13) per dose SII, started manufacturing a nasal COVID-19 vaccine Has completed preclinical animal studies Phase I in the UK by end of 2020 Brazil Amazon resurgence https://www.reuters.com/article/us-health-coronavirus-brazil-manaus-idUSKBN26I0I4 Brasilia, (1.8 million) closed bars, river beaches, parties banned Manaus Never imposed a full lockdown COVID-19 herd immunity in the Brazilian Amazon (Sao Paulo’s Institute of Tropical Medicine) https://www.medrxiv.org/content/10.1101/2020.09.16.20194787v1 Cases increased quickly during March and April Declined slowly from May to September Antibody tests, 44% - 66% Not wearing masks, packing into bars and attending parties Infections now increasing Netherlands https://www.reuters.com/article/us-health-coronavirus-netherlands-tally-idUSKBN26K27H Cases, + 3,011 (a daily record) (National Institute for Health, RIVM) The number of cases rose sharply in almost all regions and in all age groups

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