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Explore President Trump's medications in detail with 388,829 views, 10,209 likes, and 3,415 comments. Experience the impact of this video content that has captured audience attention.

Current infections UK Cases, + 20, 641 Active, 264,034 US Cases, + 301,438 (last 7 days) President Trump’s meds Dr. Sean Conley Oxygen dropped twice Did not need oxygen for long at all Slight cough Viral load not established yet Fever Now No fever, reducing meds for past 72 hours No evidence of live virus Normally 10 days after day 1 Most viral shedding in first 5 days Not out of the woods yet https://www.bostonglobe.com/2020/10/05/nation/look-three-medications-president-trump-is-taking-treat-covid-19-what-they-do/ Remdesivir Regeneron treatment, REGEN-CoV-2 Dexamethasone Zinc Vitamin D Famotidine Melatonin Daily aspirin Remdesivir 5 days, intravenous FDA emergency approval for anyone in hospital with COVID Probably needs to be given very early Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19, A Randomized Clinical Trial, (JAMA, 21st August) https://jamanetwork.com/journals/jama/fullarticle/2769871 n = 584 Moderate COVID-19 Remdesivir group and standard care group 7-point ordinal scale on study day 11 5 day course, statistically significant difference in clinical status Difference was of uncertain clinical importance 10 day course, no statistical difference from standard care Antibody therapy (Friday 2nd October, morning) MABs are produced from cell cultures REGEN-CoV-2 8 grams 2 antibodies which attach to the spike protein 2 monoclonal antibodies Only available for trial use Given as compassionate use Passive immunity Probably lasts for 4 to 6 weeks Recovery trial https://www.recoverytrial.net RECOVERY COVID-19 phase 3 trial to evaluate Regeneron’s REGN-COV2 investigational antibody cocktail in the UK https://www.recoverytrial.net/news/recovery-covid-19-phase-3-trial-to-evaluate-regeneron2019s-regn-cov2-investigational-antibody-cocktail-in-the-uk 14th September 2,000 patients in each group Dexamethasone Recovery trial Early use may reduce immune response Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report, (NEJM, 17th July https://www.nejm.org/doi/10.1056/NEJMoa2021436 Experimental group, n = 2,104 Standard care group, n = 4,321 In patients hospitalized with Covid-19, Dexamethasone reduced 28-day mortality among those who were receiving either invasive mechanical ventilation or oxygen alone No benefit in those receiving no respiratory support. Greatest benefit in those being ventilated Zinc The Role of Zinc in Antiviral Immunity, (Advances in Nutrition, July 2019) https://academic.oup.com/advances/article/10/4/696/5476413 Hundreds of key enzymes Transcription factor Second-most abundant trace metal in the body Zinc deficiency results in a compromised immune system Required to mount an effective antiviral response Direct antiviral properties (e.g. influenza) Critical in generating innate and acquired antiviral responses The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis (Frontiers in Immunology, July, 2020) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365891/ Preserve natural tissue barriers Respiratory epithelium, preventing pathogen entry Probably useful, especially in zinc deficiency Studies are needed Testing the effect of zinc as therapeutic option for established disease Cost-efficient Globally available Simple to use Little to no side effects Vitamin D Spanish clinical trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456194/ Calcifediol group, 2% required admission to the ICU Control group 50% admitted to ICU Famotidine H2-receptor antagonists Cimetidine, ranitidine Melatonin Hormone Pineal gland Regulates the sleep–wake cycle Interacts with the immune system Reduces inflammation Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19 https://clinicaltrials.gov/ct2/show/NCT04474483 Phase 2 Daily aspirin 300 mg 600 mg 900 mg Low dose https://www.nhs.uk/medicines/low-dose-aspirin/ 75 mg day Statins Talk to Karen about art books like the one she sent me https://www.youtube.com/redirect?redir_token=QUFFLUhqa1dFejhrQ2lJT2szOWJ0elJtR1JBaVZFQktRd3xBQ3Jtc0trVnUzMnFmQkhMdUt6WTlCRGtoNzg4MmpPOFZvSHRlR0xiclpicllUYU9OR1hoTmlES3lNWGVPQnZkdHBDR0gwanIxdXlYcWQ5UzZHWm1acHNITTY3Z2MzNnlFWVdaY0RqZHFnanEtcUVYQWFtUXc0TQ%3D%3D&q=http%3A%2F%2Fwww.spellboundbookart.co.uk%2F&stzid=UgxMhgA9qvEVlTtzD1p4AaABAg.9ET35P3BlFY9ET8tC1HdZH&event=comments

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